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Clinical trial uses prime editing to alter DNA directly in a patient

Nature reported that a clinical trial used CRISPR prime editing to alter DNA directly inside a person for the first time.

A clinical trial has used CRISPR prime editing to alter DNA directly in a person's body, Nature reported. The treatment is being tested for a genetic disease that can affect the liver and nervous system.

The report describes an early clinical application of the precision gene-editing technique; its safety and effectiveness will require continued trial results.

Sources

  1. Nature — A first for CRISPR: powerful prime editing alters DNA directly in the human body ↗