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Mouse study identifies granzyme K as a contributor to age-related tissue damage

Researchers reported that older mice lacking granzyme K had less tissue damage and better heart, liver, and kidney function.

A study highlighted by Nature found that removing the enzyme granzyme K in aged mice was associated with reduced scarring and damage in several organs.

The work identifies a possible biological target for research on age-related tissue decline, but it was conducted in mice and does not establish a treatment for people.

Sources

  1. Nature — Found: a protein that drives ageing without unleashing inflammation ↗