Mouse study links intestinal IgA to lower susceptibility to colorectal tumors
A Nature study reported that intestinal immunoglobulin A helped regulate colon-cell growth and reduced colorectal tumor susceptibility in mouse models.
Researchers reported that mice lacking intestinal immunoglobulin A, or IgA, had increased colon-cell proliferation and greater susceptibility to several models of colorectal cancer. Oral IgA treatment reduced proliferation and protected against tumors in the study.
The research was conducted in mouse and laboratory models, so it does not establish a treatment or prevention method for people.