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Study finds disrupted blood-brain barrier protein transport in mice modeling early Alzheimer's disease

Researchers reported that blood-brain barrier transport of some proteins was disrupted in mice modeling early-stage Alzheimer's disease.

A research team catalogued nearly 100 proteins that can cross the blood-brain barrier and help maintain brain health, Nature reported. In mice with a neurological disease model, transport of some of those proteins was impaired.

The findings describe a mechanism in an animal model and do not establish a treatment or cause of Alzheimer's disease in people.

Sources

  1. Nature — New culprit in early Alzheimer’s: Blood–brain barrier blocks protective proteins ↗